Tat protein

Tat protein
Transactivator protein from lentiviruses, notably HIV; sequence-specific RNA binding protein that recognizes TAR RNA. Will induce endothelial cell migration and invasion in vitro and rapid angiogenesis in vivo. Peptides from this protein are potent neurotoxins, implying a possible route for HIV-mediated toxicity.

Dictionary of molecular biology. 2004.

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